Ibuprofen was more protective against asthma morbidity than acetaminophen in asthmatic children with fever

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Ibuprofen was more protective against asthma morbidity than acetaminophen in asthmatic children with fever.

Patients 1879 children between 6 months and 12 years of age (median age 46 mo, 62% boys) who were being treated for asthma with a -agonist, theophylline, or inhaled steroid and had a febrile illness. Exclusion criteria were known sensitivity to acetaminophen, ibuprofen, aspirin, or any non-steroidal anti-inflammatory drug (NSAID); nasal polyps; angioedema; or bronchospastic reactivity to aspiri...

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ACP Journal Club. Ibuprofen plus acetaminophen reduced knee pain in the short-term more than acetaminophen but not ibuprofen.

In a head-to-head trial, Doherty and colleagues compared monotherapies (OTC acetaminophen or ibuprofen) with a combination of both in persons with chronic knee pain. 85% of participants had osteoarthritis by clinical criteria. Unfortunately, the report does not provide information on participants’ general level of functioning or comorbid conditions. Moreover, it’s unclear whether the results ar...

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acetaminophen and ibuprofen in controlling fever and preventing convulsion in children with febrile seizure

background febrile seizure is one of the most prevalent pediatric diseases. an essential part of the physicians’ efforts is to decreasing the parents’ stress level when they confront febrile diseases in children. objectives this study was performed to compare the effects of acetaminophen and ibuprofen on controlling fever and preventing seizures in children with febrile seizure. patients and me...

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Comparison of the Effects of Acetaminophen Plus Ibuprofen to Treat Fever Than any of the Two Alone in Febrile Children

Background: Fever is a natural response of the host to infection and a normal part of children’s infectious disease. Objectives: The purpose of the study was comparison of the combined treatment of acetaminophen and ibuprofen compact with each treatment alone. Methods: This Double-blind clinical trial study was done on 540 children with 38°C to 41°C as body temperature. Eligible children after ...

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Effects of Acetaminophen consumption in asthmatic children

BACKGROUND Acetaminophen exposure might be associated with increasing risk of asthma prevalence and other atopic disorders over recent decades. The present study aimed to investigate the association between acetaminophen exposure and the risk of developing childhood asthma. METHODS A case - control study was undertaken between March and September 2010 in Urmia district north west of Iran. Sub...

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ژورنال

عنوان ژورنال: Evidence-Based Medicine

سال: 2002

ISSN: 1356-5524

DOI: 10.1136/ebm.7.6.182